Professor Stefan Seewald​, GastroZentrum Hirslanden, Zurich This case presents an incidentally detected squamous cell carcinoma. NBI is considered most beneficial for detection and characterization. TXI in combination with Lugol was helpful to delineate the lesion. TXI improves the delineation with Lugol compared to white light. Scope:GIF-EZ1500 Case: Squamous Cell Carcinoma Organ: Esophagus Patient information: M, 74 Medical history: Smoke