In the coming years, Canada is anticipating accepting the highest numbers of permanent residents in its history; upwards of 465,000 people annually. Currently, about 22% of Canadians were born in another country. Despite the continued importance of im/migrants to Canada, their health is rarely understood through a social determinants of health (SDOH) lens. This presentation will describe im/migration in relation to the SDOH, review the immigration database housed at the Institute for Clinical Evaluative Sciences (ICES) and describe COVID-19 vaccine uptake using disaggregated data from this database and touch on community engagement strategies. To appreciate the diversity of immigrants and the potential complexity involved with improving vaccine uptake, known barriers, facilitators, and determinants of vaccine uptake among migrants more broadly will also be reviewed.