CACA guidelines for holistic integrative management of gastric cancer

Malignant soft tissue tumours rarely arise in the space between the peritoneum and the posterior abdominal wall that contains many significant organs and structures. These retroperitoneal soft tissue sarcomas (RPSs) are mainly treated with surgery, but since wide resection is usually unfeasible, they frequently recur due to its large size, indistinct tumour borders, anatomic constraints and the thinness of the overlying peritoneum. In recent decades, the role of emerging therapeutic strategies, such as more extended surgery and administration of radiotherapy and/or chemotherapy before or after surgery, to improve oncological outcome in primary localised RPS has been extensively investigated. In this review, the recent data on the evolving multidisciplinary management of primary localised RPS are comprehensively discussed. The heterogeneity of RPS, with their different histological subtypes and biological behaviour, renders a standard therapeutic ‘one-size-fits-all’ approach inappropriate, and treatment should be modified according to histological type and malignancy grade of these tumours.

Source：Holistic Integrative Oncology

Source：Holistic Integrative Oncology