Coagulation Cascade

2023-5-19 16:12

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Let’s talk about the Coagulation Cascade involved in Secondary Hemostasis. Basically, there are three interrelated pathways of coagulation, each representing a unique series of biochemical reactions. These pathways are the Intrinsic, Extrinsic, and the common pathway. Each pathway is activated by a different mechanism. The activation of the Intrinsic pathway occurs when a blood vessel is injured, exposing the subendothelial basement membrane and collagen. Both surfaces promote coagulation.

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