PHO Microbiology Rounds - Progress and Challenges in Implementing a Tuberculosis Genomic Epidemiology
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2023-11-9 11:04
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Genotyping of Mycobacterium Tuberculosis using methods such as Mycobacterial Interspersed Repetitive Unit-Variable Number of Tandem Repeats (MIRU-VNTR) has greatly enhanced traditional contact tracing efforts and is a valuable tool. However, the emerging field of genomic epidemiology, which relies on whole genome sequencing (WGS), is significantly more powerful in determining both the direction and timing of person-to-person spread of tuberculosis (TB). Yet many public health laboratories are challenged to fully implement TB genomic epidemiology programs.
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