Diagnostic tools in Hematology are Routine staine and morphology, cytochemistry, immunophenotyping, cytogeneteics, molecular biology. Cytochemistry uses special stains that are useful for classifying and differentiating types of leukemias. Leukocyte Alkaline Phosphatase is useful in differentiating Leukemoid reaction (Increased alkaline phosphatase activity) from Chronic Myelogenous Leukemia (decreased activity). Myeloperoxidase (MPO) is a lysosomal enzyme found in the primary granules of granulocytic cells . SBB is a fat soluble dye that stains intra cellular lipids such as neutral fat, cholesterol, phospholipids.